The Pikachu Family
Let's start this list off the right way. The one Pokemon that everyone is familiar with, whether or not they know anything about the series, is Pikachu. This cute electric mouse is the series' mascot, and the one Pokemon that damn near everyone wishes they could have following them around. Artissx from DeviantArt did an excellent job turning the series' telltale, blushing mouse into something that could be wandering around in your backyard.
Image Credit: Artissx DeviantArt