Let's just start with this one. Studios are closing more and more, even in what is ostensibly a period of economic recovery. Even within huge companies like EA and Capcom, studios are being shut down with little or no previous notice, leaving hundreds out of work.
Just look at Capcom Vancouver, which was working on several projects until Capcom up and decided to move all its operations back to Japan. It ate a massive loss, canceled all of the studio's projects, and laid everyone off. (The Telltale Games situation was ever worse, more on that later.) If one or two games not being massive hits results in everyone being fired despite past successes, that's a big problem. All or nothing is a problem! Right?